Association of Use of a Meningococcus Group B Vaccine With Group B Invasive Meningococcal Disease Among Children in Portugal

Artigo da autoria de Fernanda M. P. Rodrigues, Robin Marlow, Maria João Simões et al publicado no JAMA

Key Points
Question  Among children in Portugal, was there an association between receipt of a 4-component meningococcus group B vaccine (4CMenB) and group B invasive meningococcal disease?

Findings  In this matched case-control study that included 299 children, the likelihood of full vaccination with 4CMenB among children old enough to be fully immunized was significantly lower among cases with group B invasive meningococcal disease compared with controls without invasive meningococcal disease (odds ratio, 0.21).

Meaning  During the first 5 years of vaccine availability in Portugal, full vaccination with 4CMenB was less likely among children who developed group B invasive meningococcal disease compared with matched controls.

Leia aqui o artigo completo (apenas em inglês).

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