A breast cancer diagnosis can greatly impact many young women and trigger a series of psychological and social challenges, particularly a fear of death or recurrence. This type of fear can cause physical and mental disorders affecting quality of life (QOL) in those with breast cancer. Endocrine therapy (ET) has also been associated with the worsening of anxiety symptoms. The precipitating factors must be recognized and identified in order to develop appropriate strategies for these patients. Both QOL and the impact of ET can be measured through questionnaires. The Functional Assessment of Cancer Treatment (FACT) and its endocrine subscale, FACT-ES v4, are validated QOL questionnaires specific to women with both breast cancer and endocrine symptoms.

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