Severe Thrombocitopenia Induced by Fenofibrate

Authors

  • Ana Clara Serviço de Medicina Interna. Centro Hospitalar Universitário do Algarve. Faro. https://orcid.org/0000-0002-5587-0842
  • Tiago Martins Serviço de Medicina Interna. Centro Hospitalar Universitário do Algarve. Faro.
  • Alexandra Martins Serviço de Medicina Interna. Centro Hospitalar Universitário do Algarve. Faro.
  • Ana Baptista Serviço de Medicina Interna. Centro Hospitalar Universitário do Algarve. Faro.
  • Mário Lázaro Serviço de Medicina Interna. Centro Hospitalar Universitário do Algarve. Faro.

DOI:

https://doi.org/10.20344/amp.11354

Keywords:

Fenofibrate/adverse effects, Purpura, Thrombocytopenic, Idiopathic/chemically induced

Abstract

Drug-induced thrombocytopenia is a common entity in clinical practice. However, having in consideration the severity of the case, it becomes imperative to distinguish non-immune thrombocytopenia from the po-tentially life-threatening immune-mediated forms. The authors report a rare clinical case of a 79-year-old man presenting with purpuric rash and gingival hemorrhage while on fenofibrate treatment (sixth day). The evolu-tion was favorable after drug removal and corticosteroid administration. Drug-associated thrombocytopenia is reported by manufacturers as an extremely rare event. This is the second case report of immune throm-bocytopenia to fenofibrate. The first event was reported for publication in 2015.

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Published

2020-01-03

How to Cite

1.
Clara A, Martins T, Martins A, Baptista A, Lázaro M. Severe Thrombocitopenia Induced by Fenofibrate. Acta Med Port [Internet]. 2020 Jan. 3 [cited 2024 Mar. 29];33(1):58-61. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/11354

Issue

Section

Case Report