Neonatal Seizures in a Tertiary Neonatal Intensive Care Unit

Authors

  • Andreia Lopes Serviço de Neonatologia. Hospital São João. Porto. Portugal.
  • Ana Vilan Serviço de Neonatologia. Hospital São João. Porto. Portugal.
  • Maria Beatriz Guedes Serviço de Neonatologia. Hospital São João. Porto. Portugal.
  • Hercília Guimarães Serviço de Neonatologia. Hospital São João. Porto. Portugal.

DOI:

https://doi.org/10.20344/amp.1353

Abstract

Introduction: Seizures are frequent in the neonatal period. They can be idiopathic, be caused by organic brain anomalies or by metabolicdisturbances.Objective: Evaluation of the etiologic diagnosis and clinical evolution of the newborns with neonatal seizures admitted at one tertiaryneonatal intensive care unit.Material and Methods: Retrospective review of the clinical files of the newborns with neonatal seizures, during a period of eight years.Results: Neonatal seizures occurred in 91 cases. Seventy nine (86.8%) received anticonvulsant therapy during clinical seizure. Imageand/or electrophysiological studies were performed in the majority of newborns (86.8%). Etiology was identified in 51.6% of the 91cases studied, being the more frequent situations: central nervous system bleeding (11 cases), hypoxic-ischemic encephalopathy (10cases) and electrolytes disturbances (7 cases). Mortality rate was 16.5%. The newborns followed in our hospital had good neurodevelopment,in 70.2% of cases but in 10.6% was detected important neurodevelopment impairment, including cerebral palsy.Conclusions: Anomalies in the cranial ultrasound and in the electroencephalography were correlated with clinical evolution. They stillare first line exams in the initial approach to this pathology.

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Published

2013-01-28

How to Cite

1.
Lopes A, Vilan A, Guedes MB, Guimarães H. Neonatal Seizures in a Tertiary Neonatal Intensive Care Unit. Acta Med Port [Internet]. 2013 Jan. 28 [cited 2022 Dec. 7];25(6):368-74. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/1353