Severe acute hepatitis C with spontaneous cure.

Margarida Marques, Hélder Cardoso, Ana Maria Horta Vale, Joanne Lopes, Guilherme Macedo


Hepatitis C virus (HCV) is responsible for 20% of all cases of acute hepatitis. However, acute C infection isn't usually recognized in clinical practice, once most of the patients are asymptomatic and, in rare cases, the acute infection can progress to a fulminant form. In 40% of HCV infections, the mode of transmission persist unknown. Nosocomial transmission is, nowadays, recognized as a way of infection. Herein, we describe a female patient, with 54 years old, with an acute C hepatitis, symptomatic, with hepatic failure. She had no risky behaviours, just a previous hospital admission 5 weeks before. The patient was kept under surveillance with clinical improvement: at 10(th) week HCV viremia was negative.

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