Campylobacter jejuni Pericarditis: A Case Report
Keywords:Agammaglobulinemia, Campylobacter Infections, Campylobacter jejuni, Pericarditis
Campylobacter jejuni is one of the most common causes of enteritis. In rare cases, extraintestinal infection can occur, with a handful of cases of cardiac involvement, of which the pathophysiological mechanism is unclear. We report a case of pericarditis in a patient with X-linked agammaglobulinemia presenting with chronic diarrhea and chest pain who evolved to cardiac tamponade, requiring a pericardial window and a long course of broad-spectrum antibiotics. To the best of our knowledge, this is the third case of pericarditis caused by Campylobacter jejuni reported in the literature, the second in a patient with X-linked agammaglobulinemia. Despite its rarity, this case serves as a reminder of Campylobacter as a potential cause of cardiac inflammation for clinicians treating pericarditis/myocarditis, especially in patients with a history of diarrhea or immunosuppression.
Allos BM, Iovine NM, Blaser MJ. Campylobacter jejuni and related species. In: Bennett J, Dolin R, Blaser MJ, editors. Mandell’s, Douglas’ and Bennett’s principles and practice of infectious diseases. 9th ed. Philadelphia: Elsevier; 2019.
Contreras-Omaña R, Escorcia-Saucedo AE, Velarde-Ruiz Velasco JA. Prevalence and impact of antimicrobial resistance in gastrointestinal infections: a review. Rev Gastroenterol México. 2021;86:265-75.
Bester LA, Essack SY. Observational study of the prevalence and antibiotic resistance of campylobacter spp. from different poultry production systems in KwaZulu-Natal, South Africa. J Food Prot. 2012;75:154-9.
Blaser MJ, Berkowitz ID, LaForce FM, Cravens J, Reller LB, Wang WL. Campylobacter enteritis: clinical and epidemiologic features. Ann Intern Med. 1979;91:179-85.
Van der Hilst JC, Smits BW, Van der Meer JW. Hypogammaglobulinaemia: cumulative experience in 49 patients in a tertiary care institution. Neth J Med. 2002;60:140-7.
Blaser MJ, Smith PF, Repine JE, Joiner KA. Pathogenesis of Campylobacter fetus infections. J Clin Invest. 1988;81:1434-44.
Uzoigwe C. Campylobacter infections of the pericardium and myocardium. Clin Microbiol Infect. 2005;11:253-5.
Kotilainen P, Lehtopolku M, Hakanen AJ. Myopericarditis in a patient with Campylobacter enteritis : a case report and literature review. Scand J Infect Dis. 2006;38:549-52.
Hessulf F, Ljungberg J, Johansson P, Lindgren M, Engdahl J. Campylobacter jejuni-associated perimyocarditis : two case reports and review of the literature. BMC Infect Dis. 2016;16:1-7.
Hannu T, Matiila L, Rautelin H, Siitonen A. Three cases of cardiac complications associated with Campylobacter jejuni infection and review of the literature. Eur J Clin Microbiol Infect Dis. 2005;24:619-22.
Rodríguez-Alvarez R, Goikoetxea J, García M, Figueras Y, Hernández L, Montejo M. Infecciones endovasculares por Campylobacter : a propósito de dos casos. Rev Española Quimioter. 2014;27:127-9.
Rafi A, Matz J. An unusual case of Campylobacter jejuni pericarditis in a patient with X-linked agammaglobulinemia. Ann Allergy Asthma Immunol. 2001;89:362-7.
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