deficiency of growth hormone in children. Re-evaluation after therapeutic completion.

Authors

  • T Martins Serviço de Endocrinologia, Diabetes e Metabolismo, Hospitais da Universidade de Coimbra, Coimbra.
  • M Bastos
  • P Leitão
  • L Barros
  • L Ruas
  • C Batista
  • S Paiva
  • M Carvalheiro
  • M M Ruas

DOI:

https://doi.org/10.20344/amp.1802

Abstract

To assess GH secretion in young adults treated with GH replacement therapy in childhood.From the 38 patients who concluded treatment with GH, we studied 20 (52.6%), 9 girls and 11 boys. Thirteen had Growth Hormone Deficiency (GHD)-65%, while 7 had Multiple Pituitary Hormone Deficiency (MPHD)-35%. The patients were retested within 6 months to 6 years after completing GH therapy. The mean age (+/- SD) at retesting was 18.1 +/- 2.6 years for those with GHD and 20.8 +/- 2.8 for those with MPHD. At reassessment we performed two provocative tests: insulin tolerance test (ITT) and clonidine test.Seven of the 20 patients retested, retained GH deficiency. Of the 13 patients with GHD, only one maintained the deficiency, while of the 7 patients with MPHD, 6 maintained the deficiency.Young adults with GH deficiency treated with this hormone should be retested in order to identify those who are truly GH insufficient adults and may benefit from replacement therapy.

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How to Cite

1.
Martins T, Bastos M, Leitão P, Barros L, Ruas L, Batista C, Paiva S, Carvalheiro M, Ruas MM. deficiency of growth hormone in children. Re-evaluation after therapeutic completion. Acta Med Port [Internet]. 2000 Dec. 30 [cited 2024 Dec. 25];13(5-6):283-5. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/1802

Issue

Vol. 13 No. 5-6 (2000): Setembro-Dezembro

Section

Arquivo Histórico

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