Consensus Guidelines for the Management of Abnormal Cervical Cancer Screening Tests by the SPCPTGI

Authors

  • Amélia Pedro Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital CUF Sintra. Sintra. https://orcid.org/0000-0002-6415-1890
  • Amália Pacheco Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Centro Hospitalar Universitário do Algarve. Unidade Faro. Faro.
  • Rita Sousa Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Instituto Português de Oncologia Francisco Gentil. Coimbra.
  • Gustavo Mendinhos Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital Beatriz Ângelo. Loures.
  • Mariana Miranda Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital CUF Sintra. Sintra; Hospital Professor Doutor Fernando Fonseca. Amadora.
  • Cecília Urzal Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Centro Hospitalar Universitário do Algarve. Unidade Portimão. Portimão.
  • Virgínia Monteiro Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital da Luz. Lisboa.
  • Teresa Fraga Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital CUF Sintra. Sintra; Hospital CUF Descobertas. Lisboa.
  • Daniel Pereira da Silva Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital CUF Coimbra. Coimbra; Instituto Médico de Coimbra. Coimbra.
  • Tereza Paula Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Maternidade Dr. Alfredo da Costa. Centro Hospitalar Universitário de Lisboa Central. Lisboa.
  • Isabel Oliveira Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Hospital Dr. Nélio Mendonça. Funchal. Madeira.
  • José Cabral Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Centro Materno Infantil do Norte. Centro Hospitalar Universitário do Porto. Porto.
  • José Fonseca Moutinho Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Coimbra; Faculdade de Ciências da Saúde. Universidade da Beira Interior. Covilhã.

DOI:

https://doi.org/10.20344/amp.18776

Keywords:

Colposcopy, Human Papillomavirus, Screening, Squamous Intraepithelial Lesions, Uterine Cervical Neoplasms

Abstract

Cervical cancer is one of the most common types of cancer in women. Cervical cancer screening is needed for the detection and treatment of cervical neoplastic lesions that can evolve to neoplasia and to reduce the incidence of cervical cancer. Recently, changes were made to increase the efficiency of the screening process such as employing the human papilloma virus detection test as the gold standard for cervical cancer screening and acknowledging the importance of adapting clinical practice to consider the risk of developing this neoplasia. Considering this paradigm shift, new clinical practice guidelines are now needed. For this purpose, a group of experts analyzed and discussed the most recent literature, defining recommendations and proposing clinical practice guidelines that focus on risk stratification, diagnostic evaluation, and on the therapeutical approach and follow-up of women with altered screening results. The aim of this article is to guide clinical practice regarding actions to take in face of altered results of cervical cancer screening and, consequently, to improve the secondary prevention of this condition.

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References

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-249. DOI: https://doi.org/10.3322/caac.21660

International Agency for research on Cancer - Global Cancer Observatory 2020. Estimated age-standardized incidence rates (World) in 2020, all cancers, both sexes, all ages. Disponível em https://gco.iarc.fr/today/online-analysis-map?v=2020.

World Health Organization. Global strategy to accelerate the elimination of cervical cancer as a public health problem 2020.

Secção Portuguesa de Colposcopia e Patologia do Trato Genital Inferior da Sociedade Portuguesa de Ginecologia (SPCPTGI-SPG). Livro de Consenso Sobre Lesões Intraepiteliais do Colo do Útero, Vulva e Vagina. 2014.

Harbour R, Miller J. A new system for grading recommendations in evidence based guidelines. BMJ. 2001;323:334-336. DOI: https://doi.org/10.1136/bmj.323.7308.334

Perkins RB, Guido RS, Castle PE, Chelmow D, Einstein MH, Garcia F, et al. 2019 ASCCP Risk-Based Management Consensus Guidelines for Abnormal Cervical Cancer Screening Tests and Cancer Precursors. J Low Genit Tract Dis. 2020;24:102-131. DOI: https://doi.org/10.1097/LGT.0000000000000525

Wright TC, Jr., Stoler MH, Behrens CM, Apple R, Derion T, Wright TL. The ATHENA human papillomavirus study: design, methods, and baseline results. Am J Obstet Gynecol. 2012;206:46.e41-46.e11. DOI: https://doi.org/10.1016/j.ajog.2011.07.024

Gage JC, Hanson VW, Abbey K, Dippery S, Gardner S, Kubota J, et al. Number of cervical biopsies and sensitivity of colposcopy. Obstet Gynecol. 2006;108:264-272. DOI: https://doi.org/10.1097/01.AOG.0000220505.18525.85

Song Y, Zhao YQ, Zhang X, Liu XY, Li L, Pan QJ, et al. Random biopsy in colposcopy-negative quadrant is not effective in women with positive colposcopy in practice. Cancer Epidemiol. 2015;39:237-241. DOI: https://doi.org/10.1016/j.canep.2015.01.008

Massad LS, Einstein MH, Huh WK, Katki HA, Kinney WK, Schiffman M, et al. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. Obstet Gynecol. 2013;121:829-846. DOI: https://doi.org/10.1097/AOG.0b013e3182883a34

Darragh TM, Colgan TJ, Cox JT, Heller DS, Henry MR, Luff RD, et al. The Lower Anogenital Squamous Terminology Standardization Project for HPVAssociated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopyand Cervical Pathology. Arch Pathol Lab Med. 2012;136:1266-1297. DOI: https://doi.org/10.5858/arpa.LGT200570

Massad LS, Einstein MH, Huh WK, Katki HA, Kinney WK, Schiffman M, et al. 2012 updated consensus guidelines for the management of abnormal cervical cancer screening tests and cancer precursors. J Low Genit Tract Dis. 2013;17:S1-s27. DOI: https://doi.org/10.1097/LGT.0b013e318287d329

Partridge EE, Abu-Rustum N, Campos S, Fahey PJ, Greer BE, Lele SM, et al. Cervical cancer screening. J Natl Compr Canc Netw. 2008;6:58-82. DOI: https://doi.org/10.6004/jnccn.2008.0007

Partridge EE, Abu-Rustum NR, Campos SM, Fahey PJ, Farmer M, Garcia RL, et al. Cervical cancer screening. J Natl Compr Canc Netw. 2010;8:1358-1386. DOI: https://doi.org/10.6004/jnccn.2010.0103

ACOG Practice Bulletin No. 99: management of abnormal cervical cytology and histology. Obstet Gynecol. 2008;112:1419-1444. DOI: https://doi.org/10.1097/AOG.0b013e318192497c

Published

2023-01-23

How to Cite

1.
Pedro A, Pacheco A, Sousa R, Mendinhos G, Miranda M, Urzal C, Monteiro V, Fraga T, Pereira da Silva D, Paula T, Oliveira I, Cabral J, Fonseca Moutinho J. Consensus Guidelines for the Management of Abnormal Cervical Cancer Screening Tests by the SPCPTGI. Acta Med Port [Internet]. 2023 Jan. 23 [cited 2024 Nov. 22];36(4):285-9. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/18776

Issue

Section

Guidelines