Effectiveness of Neuropsychological Rehabilitation in the Recovery of Executive Deficits in Patients with Alcohol Use Disorder: A Systematic Review Protocol
DOI:
https://doi.org/10.20344/amp.19804Keywords:
Alcoholism, Alcohol Use Disorder, Cognitive Rehabilitation, Executive FunctioningAbstract
Introduction: Changes in executive functions associated with alcohol consumption are frequently found in alcohol use disorder. Neuropsychological rehabilitation can play an essential role as an effective treatment in the recovery from these deficits, leading to the maintenance of abstinence. However, there are still some uncertainties regarding its impact on the recovery of deficits in executive functions. Our purpose is to present a protocol for a systematic review aiming to assess which neuropsychological rehabilitation programs are effective in the recovery of executive deficits in patients with alcohol use disorder.
Methods: We will search the following databases: PubMed, Cochrane Library (CENTRAL), Web of Science, and Scopus, as well as the list of references of the identified studies. Screening, data extraction, and synthesis, as well as evaluation of the risk of bias, will be carried out by two reviewers independently, using ROBINS-I and RoB 2. Disagreements will be resolved using a third additional reviewer. Primary outcomes will correspond to changes in executive functions, following a neuropsychological rehabilitation program in patients with alcohol use disorder. The evidence will be synthesized using a narrative description of neuropsychological rehabilitation programs and the indicators of their effectiveness will be identified. The neuropsychological rehabilitation programs for executive functions will be assessed considering their different components and their impact on the recovery of these functions. The review described in this protocol will allow the development of guidelines for the design of more effective rehabilitation programs for clinical populations with alcohol use disorder.
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Caneva S, Ottonello M, Torselli E, Pistarini C, Spigno P, Fiabane E. Cognitive impairments in early-detoxified alcohol-dependent inpatients and their associations with socio-demographic, clinical and psychological factors: an exploratory study. Neuropsychiatr Dis Treat. 2020;16:1705-16. DOI: https://doi.org/10.2147/NDT.S254369
Le Berre AP, Fama R, Sullivan EV. Executive functions, memory, and social cognitive deficits and recovery in chronic alcoholism: a critical review to inform future research. Alcohol Clin Exp Res. 2017; 41:1432-43. DOI: https://doi.org/10.1111/acer.13431
Maillard A, Poussier H, Boudehent C, Lannuzel C, Vicente A, Vabret F, et al. Short-term neuropsychological recovery in alcohol use disorder: a retrospective clinical study. Addict Behav. 2020;105:106350. DOI: https://doi.org/10.1016/j.addbeh.2020.106350
Crespi C, Galanda C, Manera M, Basso G, Poggi P, Canessa N. Executive impairment in alcohol use disorder reflects structural changes in large-scale brain net-works: a joint independent component analysis on gray-matter and white-matter features. Front. Psychol. 2019;10:2479. DOI: https://doi.org/10.3389/fpsyg.2019.02479
Loime L, Guglielmo R, Affini GF, Quatrale M, Martinotti G, Callea A, et al. Neuropsychological performance in alcohol dependent patients: a one-year longitudinal study. Psychiatry Investig. 2018;15:505-13. DOI: https://doi.org/10.30773/pi.2017.09.27.1
Nowakowska-Domagala K, Jablkowska-Gorecka K, Mokros L, Koprowicz J, Pietras T. Differences in the verbal fluency, working memory and executive functions in alcoholics: short-term vs. long-term abstainers. Psychiatry Res. 2017;249:1-8. DOI: https://doi.org/10.1016/j.psychres.2016.12.034
Velayudhan R, Saraswathy S. Neuropsychological functions in short- and long-term alcohol abstinence. Ind J Priv Psychiatry. 2020;14:26-9. DOI: https://doi.org/10.5005/jp-journals-10067-0054
Kaur P, Sidana A, Malhotra N, Gupta A. Effects of abstinence of alcohol on neurocognitive functioning in patients with alcohol dependence syndrome. Asian J Psychiatr. 2020;50:101997. DOI: https://doi.org/10.1016/j.ajp.2020.101997
Bernadim F, Maheut-Bosser A, Paille F. Cognitive impairments in alcohol-dependent subjects. Front. Psychiatry. 2014;5:78. DOI: https://doi.org/10.3389/fpsyt.2014.00078
Peterson M, Patterson B, Pillman B, Battista M. Cognitive recovery following alcohol detoxification: A computerised remediation study. Neuropsychol Rehabil. 2010;12: 63-74. DOI: https://doi.org/10.1080/09602010143000167
Loeber S, Duka T, Márquez H, Nakovics H, Heinz A, Mann K, et al. Effects of repeated withdrawal from alcohol on recovery of cognitive impairment under abstinence and rate of relapse. Alcohol Alcohol. 2010;45:541-7. DOI: https://doi.org/10.1093/alcalc/agq065
Sampedro-Piquero P, Guevara-Miranda D, Pavón F, Serrano A, Suárez J, Fonseca F, et al. Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation. Neurosci Biobehav Rev. 2019;106:23-48 DOI: https://doi.org/10.1016/j.neubiorev.2018.11.015
Frías-Torres C, Moreno-España J, Ortega L, Barrio P, Gual A, Teixidor L. Remediation therapy in patients with alcohol use disorders and neurocognitive disorders: a pilot study. Adicciones. 2018;30:93-100 DOI: https://doi.org/10.20882/adicciones.757
Bell M, Vissicchio N, Weinstein A. cognitive training and work therapy for the treatment of verbal learning and memory deficits in veterans with alcohol use disorders. J Dual Diagn. 2016;12:83-9 DOI: https://doi.org/10.1080/15504263.2016.1145779
Bell M, Laws H, Petrakis I. Randomized controlled trial of cognitive remediation and work therapy in the early phase of substance use disorder recovery for older veterans: neurocognitive and substance use outcomes. Psychiatr Rehabil J. 2017;40:94-102 DOI: https://doi.org/10.1037/prj0000211
Kumari D, Kumar P. Efficacy of cognitive rehabilitation for patients with alcohol dependence. Int J Indian Psychol. 2020;8:1428-37.
Jones A, McGrath E, Robinson E, Houben K, Nederkoorn C, Field M. A randomized controlled trial of inhibitory control training for the reduction of alcohol consumption in problem drinkers. J Consult Clin Psychol. 2018;86:991-1004. DOI: https://doi.org/10.1037/ccp0000312
Houben K, Wiers R, Jansen A. Getting a grip on drinking behavior: training working memory to reduce alcohol abuse. Psychol Sci. 2011;22:968-75. DOI: https://doi.org/10.1177/0956797611412392
Khemiri L, Brynte C, Stunkel A, Klingberg T, Jayaram-Lindström N. Working memory training in alcohol use disorder: a randomized controlled trial. Alcohol Clin Exp Res. 2019;43:135-46. DOI: https://doi.org/10.1111/acer.13910
Bates ME, Buckman JF, Nguyen TT. A role for cognitive rehabilitation in increasing the effectiveness of treatment for alcohol use disorders. Neuropsychol Rev. 2013;23:27-47. DOI: https://doi.org/10.1007/s11065-013-9228-3
Roehrich L, Goldman M. Experience-dependent neuropsychological recovery, and the treatment of alcoholism. J Cons Clin Psychology. 1993;61:812-21. DOI: https://doi.org/10.1037/0022-006X.61.5.812
Higgins J, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, et al, editors. Cochrane Handbook for Systematic Reviews of Interventions version 6.3. Cochrane. 2022. [cited 2022 Jun 9]. Available from: https://training.cochrane.org/handbook.
Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015;4:1. DOI: https://doi.org/10.1186/2046-4053-4-1
Thomas J, Kneale D, McKenzie J, Brennan S, Bhaumik S. Chapter 2: determining the scope of the review and the questions it will address. In: Higgins J, Thomas J, Chandler J, Cumpston M, Li T, Page M, et al, editors. Cochrane Handbook for Systematic Reviews of Interventions version 6.3. Cochrane. 2022. [cited 2022 Jun 9]. Available from: https://www.training.cochrane.org/handbook.
Sterne J, Hernán M, Reeves B, Savović J, Berkman N, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919. DOI: https://doi.org/10.1136/bmj.i4919
Higgins J, Altman D, Sterne J. Chapter 8: assessing risk of bias in included studies. In Higgins J, Green S, editors. Cochrane handbook for systematic reviews of interventions version 5.1.0. Cochrane. 2011. [cited 2022 Jan 5]. Available from: https://www.handbook.cochrane.org.
Nixon S, Lewis B. Cognitive training as a component of treatment of alcohol use disorder: a review. Neuropsychology. 2019;33:822-41. DOI: https://doi.org/10.1037/neu0000575
Caetano T, Pinho M, Ramadas E, Clara C, Areosa T, Dixe M. Cognitive training effectiveness on memory, executive functioning, and processing speed in individuals with substance use disorders: a systematic review. Front Psychol. 2021;12:730165. DOI: https://doi.org/10.3389/fpsyg.2021.730165
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