The hemolytic-uremic syndrome.

Authors

  • P A Rodrigues Serviço de Medicina, Hospital Curry Cabral, Lisboa.
  • J Machado
  • O Cardoso
  • J Cruz
  • F Carvalho
  • M da Costa
  • R Proença

DOI:

https://doi.org/10.20344/amp.2140

Abstract

The microangiopathic thrombotic syndromes--thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS)--are characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal dysfunction, fever and central nervous system abnormalities. Today they are considered as two extremes of a continuous spectrum named TTP--HUS. The syndrome is an uncommon disease with a high mortality rate, despite treatment. The authors describe a case of hemolytic uremic syndrome in a young adult patient. Initially the clinical course and the first biopsy suggested a favourable prognosis, but the early recurrence with severe hypertension was followed by a fatal outcome 6 months later. Concerning this clinical case, the authors present a review of the most recent aspects of the pathogenesis and treatment of this syndrome.

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How to Cite

1.
Rodrigues PA, Machado J, Cardoso O, Cruz J, Carvalho F, da Costa M, Proença R. The hemolytic-uremic syndrome. Acta Med Port [Internet]. 1999 Jun. 30 [cited 2024 Nov. 22];12(4-6):217-22. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/2140

Issue

Section

Arquivo Histórico