The hemolytic-uremic syndrome.


  • P A Rodrigues Serviço de Medicina, Hospital Curry Cabral, Lisboa.
  • J Machado
  • O Cardoso
  • J Cruz
  • F Carvalho
  • M da Costa
  • R Proença



The microangiopathic thrombotic syndromes--thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS)--are characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal dysfunction, fever and central nervous system abnormalities. Today they are considered as two extremes of a continuous spectrum named TTP--HUS. The syndrome is an uncommon disease with a high mortality rate, despite treatment. The authors describe a case of hemolytic uremic syndrome in a young adult patient. Initially the clinical course and the first biopsy suggested a favourable prognosis, but the early recurrence with severe hypertension was followed by a fatal outcome 6 months later. Concerning this clinical case, the authors present a review of the most recent aspects of the pathogenesis and treatment of this syndrome.


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How to Cite

Rodrigues PA, Machado J, Cardoso O, Cruz J, Carvalho F, da Costa M, Proença R. The hemolytic-uremic syndrome. Acta Med Port [Internet]. 1999 Jun. 30 [cited 2023 Dec. 11];12(4-6):217-22. Available from:



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