Infection and Immunosuppression as Causes for Immune Dysfunction Presenting as Hemophagocytic Lymphohistiocytosis and Thrombotic Microangiopathy

Henrique Atalaia-Barbacena; Maria Ana Quadros Flores; Inês Matias Lopes; Margarida Guiomar; Patrícia Howell-Monteiro

doi:10.20344/amp.21969

Infection and Immunosuppression as Causes for Immune Dysfunction Presenting as Hemophagocytic Lymphohistiocytosis and Thrombotic Microangiopathy

Authors

Henrique Atalaia-Barbacena Internal Medicine Department. Hospital de Santa Maria. Unidade Local de Saúde de Santa Maria. Lisbon; Instituto de Farmacologia e Neurociências Básicas. Faculdade de Medicina. Universidade de Lisboa. Lisbon. https://orcid.org/0000-0002-2270-8275
Maria Ana Quadros Flores Infectious Diseases Department. Hospital de Santa Maria. Unidade Local de Saúde de Santa Maria. Lisbon.
Inês Matias Lopes Internal Medicine Department. Hospital de Santa Maria. Unidade Local de Saúde de Santa Maria. Lisbon.
Margarida Guiomar Internal Medicine Department. Hospital de Santa Maria. Unidade Local de Saúde de Santa Maria. Lisbon.
Patrícia Howell-Monteiro Internal Medicine Department. Hospital de Santa Maria. Unidade Local de Saúde de Santa Maria. Lisbon.

DOI:

https://doi.org/10.20344/amp.21969

Keywords:

Lymphohistiocytosis, Hemophagocytic/etiology

Abstract

N/A

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References

McClain KL, Eckstein O. Clinical features and diagnosis of hemophagocytic lymphohistiocytosis. May 2022. UpToDate. [cited 2024 June 15]. Available from: https://www.uptodate.com/contents/clinical-features-and-diagnosis-of-hemophagocyticlymphohistiocytosis?search=hemophagocytic%20lymphohistiocytosis&source=search_result&selectedTitle=1%7E150&usage_type=default&display_rank=1.

McGonagle D, Sharif K, O’Regan A, Bridgewood C. The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease. autoimmunity reviews. Autoimmun Rev. 2020;19:102537.

Meazza Prina M, Martini F, Bracchi F, Di Mauro D, Fargnoli A, Motta M, et al. Hemophagocytic syndrome secondary to SARS-Cov-2 infection: a case report. BMC Infect Dis. 2021;21:811.

Soy M, Atagündüz P, Atagündüz I, Sucak GT. Hemophagocytic lymphohistiocytosis: a review inspired by the COVID-19 pandemic. Rheumatol Int. 2021;41:7-18.

Singh S, Murad MH, Fumery M, Sedano R, Jairath V, Panaccione R, et al. Comparative efficacy and safety of biologic therapies for moderateto- severe crohn’s disease: a systematic review and network metaanalysis. Lancet Gastroenterol Hepatol. 2021;6:1002-14.

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Published

2025-01-02

How to Cite

Atalaia-Barbacena H, Quadros Flores MA, Matias Lopes I, Guiomar M, Howell-Monteiro P. Infection and Immunosuppression as Causes for Immune Dysfunction Presenting as Hemophagocytic Lymphohistiocytosis and Thrombotic Microangiopathy. Acta Med Port [Internet]. 2025 Jan. 2 [cited 2025 Jan. 7];38(1):57-60. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/21969

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Issue

Vol. 38 No. 1 (2025): January

Section

Letters to the Editor

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