Paediatric Meningioangiomatosis PD-L1+: A Case Report

Authors

  • Gabriele Gaggero Pathology Unit. Istituto di Ricovero e Cura a Carattere Scientifico. Istituto Giannina Gaslini. Genova. Italy.
  • Silvia Bozzano Division of Anatomic Pathology. Department of Integrated Surgical and Diagnostic Sciences (DISC). Scuola di Scienze Mediche e Farmaceutiche. Università di Genova. Genoa. Italy.
  • Antonia Ramaglia Neuroradiology Unit. Istituto di Ricovero e Cura a Carattere Scientifico. Istituto Giannina Gaslini. Genova. Italy.
  • Claudia Milanaccio Neuro-oncology Unit. Istituto di Ricovero e Cura a Carattere Scientifico. Istituto Giannina Gaslini. Genova. Italy.
  • Marco Pavanello Neurosurgery Unit. Istituto di Ricovero e Cura a Carattere Scientifico. Istituto Giannina Gaslini. Genova. Italy.

DOI:

https://doi.org/10.20344/amp.22276

Keywords:

Angiomatosis, Child, Immune Checkpoint Inhibitors, Meningioma

Abstract

N/A

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References

Roux A, Zanello M, Mancusi RL, Still ME, Nascimento FA, Tauziede-Espariat A, et al. Meningioangiomatosis: multimodal analysis and insights from a systematic review. Neurology. 2021;96:274-86. DOI: https://doi.org/10.1212/WNL.0000000000011372

Whiting DM, Awad IA, Miles J, Chou SS, Lüders H. Intractable complex partial seizures associated with occult temporal lobe encephalocele and meningoangiomatosis: a case report. Surg Neurol. 1990;34:318-22. DOI: https://doi.org/10.1016/0090-3019(90)90007-C

Tauziède-Espariat A, Masliah-Planchon J, Sievers P, Sahm F, Dangouloff-Ros V, Boddaert N, et al. A comprehensive histomolecular characterization of meningioangiomatosis: further evidence for a precursor neoplastic lesion. Brain Pathol. 2024;34:e13259. DOI: https://doi.org/10.1111/bpa.13259

Gaggero G, Campora M, Taietti D, Cerruti G, Lo Bue E, Truffelli M, et al. Lymphoplasmacyte-rich meningioma with hematologic signs and PD-L1 over-expression. Autops Case Rep. 2022;12:e2021394. DOI: https://doi.org/10.4322/acr.2021.394

Wang Y, Zhang C, Yan M, Ma X, Song L, Wang B, et al. PD-L1 regulates tumor proliferation and T-cell function in NF2-associated meningiomas. CNS Neurosci Ther. 2024;30:e14784. DOI: https://doi.org/10.1111/cns.14784

Chen K, Huang Z, Liu C, Ouyang Q, Yan Q, Zheng W, et al. Hsa_ circ_0004872 mitigates proliferation, metastasis and immune escape of meningioma cells by suppressing PD-L1. Metab Brain Dis. 2024;39:895-907. DOI: https://doi.org/10.1007/s11011-024-01345-4

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Published

2025-05-02

How to Cite

1.
Gaggero G, Bozzano S, Ramaglia A, Milanaccio C, Pavanello M. Paediatric Meningioangiomatosis PD-L1+: A Case Report. Acta Med Port [Internet]. 2025 May 2 [cited 2025 Dec. 9];38(5):350-1. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/22276

Issue

Vol. 38 No. 5 (2025): May

Section

Letters to the Editor

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Copyright (c) 2025 Acta Médica Portuguesa

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