Diet and risk of myocardial infarction. A case-control community-based study.

Authors

  • C Lopes Serviço de Higiene e Epidemiologia, Faculdade de Medicina do Porto, Hospital de S. João.
  • P Von Hafe
  • E Ramos
  • P B Fernando
  • M J Maciel
  • H Barros

DOI:

https://doi.org/10.20344/amp.2246

Abstract

To evaluate diet as a risk factor for myocardial infarction.Community based case-control study.University Hospital, Oporto.First time consecutive cases of acute myocardial infarction (n = 100) and 198 community controls, older than 39 years and living in Oporto, were compared.Data were collected by trained interviewers using a structured questionnaire designed to obtain information on socio-demographic, medical and behavioural aspects, emphasising the description of diet and food habits (using a semi-quantitative food frequency questionnaire). Controls were selected by random digit dialing with a participation rate of 70%. Odds ratios and 95% confidence intervals (CI) according to quartiles of nutrient ingestion were calculated using unconditional logistic regression.Female controls presented significantly higher mean intakes of protein, omega-3 fatty acids, fiber, cholesterol and vitamin C. Male controls had a significantly higher mean daily intake of fiber, vitamin C, vitamin E, and carotenes. After adjusting for age, sex, education, body mass index, ethanol, smoking and total energy intake, there was a protective effect of vitamin C (OR = 0.2, 95% CI: 0.1-0.6, for the 4th quartile), vitamin E (OR = 0.3, 95% CI: 0.1-0.9 for the 4th quartile) and total fiber (OR = 0.3, 95% CI: 0.1-0.9) for the 4th quartile). No significant effect was found for trans-fatty acids, but there was a higher risk with increased energy intake.This study showed that diet has an important independent effect on myocardial infarction, a protective independent role for anti-oxidant vitamin C and E was verified.

Downloads

Download data is not yet available.

How to Cite

1.
Lopes C, Von Hafe P, Ramos E, Fernando PB, Maciel MJ, Barros H. Diet and risk of myocardial infarction. A case-control community-based study. Acta Med Port [Internet]. 1998 Apr. 30 [cited 2024 Nov. 12];11(4):311-7. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/2246

Issue

Section

Arquivo Histórico