Retropharyngeal Metastasis: A Rare and Frequently Aggressive Presentation of Papillary Thyroid Carcinoma

Authors

  • Mariana Caldeira Serviço de Medicina Interna. Unidade Local de Saúde da Cova da Beira. Covilhã. https://orcid.org/0000-0001-5746-1041
  • Carmen Alonso Serviço de Medicina Interna. Unidade Local de Saúde da Cova da Beira. Covilhã.
  • Ana Branco Serviço de Medicina Interna. Unidade Local de Saúde da Cova da Beira. Covilhã.
  • Telma Mendes Serviço de Medicina Interna. Unidade Local de Saúde da Cova da Beira. Covilhã.
  • Paula Soares Grupo “Cancer Signalling and Metabolism”. Instituto de Investigação e Inovação em Saúde (i3S). Universidade do Porto. Porto. & Instituto de Patologia e Imunologia Molecular (Ipatimup). Universidade do Porto. Porto. & Departamento de Patologia. Faculdade de Medicina. Universidade do Porto. Porto.

DOI:

https://doi.org/10.20344/amp.24464

Keywords:

Lymphatic Metastasis, Thyroid Cancer, Papillary, Thyroid Neoplasms

Abstract

n/a.

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References

Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74:229-63. DOI: https://doi.org/10.3322/caac.21834

World Health Organization. WHO Classification of Tumours of Endocrine Organs. 5ª ed. Lyon: International Agency for Research on Cancer; 2022.

Raposo L, Morais S, Oliveira MJ, Marques AP, José Bento M, Lunet N. Trends in thyroid cancer incidence and mortality in Portugal. Eur J Cancer Prev. 2017;26:135-43. DOI: https://doi.org/10.1097/CEJ.0000000000000229

Caldeira M, Canberk S, Macedo S, Melo M, Máximo V, Soares P. Comparative analysis of follicular cell-derived thyroid carcinoma: assessing the impact of high-grade features in an advanced disease cohort. Virchows Arch. 2025;486:1305-15. DOI: https://doi.org/10.1007/s00428-025-04109-2

Amado A, Teixeira E, Canberk S, Macedo S, Castro B, Pereira H, et al. Subcentimetric papillary thyroid carcinoma with extensive lymph node and brain metastasis: case report and review of literature. Endocrinol Diabetes Metab Case Rep. 2023;2023:23-5. DOI: https://doi.org/10.1530/EDM-23-0025

Pina H, Cavaco D, Nogueira R, Leite V. Retropharyngeal lymph node metastases in papillary thyroid carcinoma: a case series and literature review. Acta Med Port. 2025;38:765-72. DOI: https://doi.org/10.20344/amp.22908

Sandler ML, Xing MH, Levy JC, Chai RL, Khorsandi AS, Gonzalez-Velazquez C, et al. Metastatic thyroid carcinoma to the parapharyngeal and retropharyngeal spaces: systematic review with seven newly reported cases describing an uncommon presentation of a common disease. Head Neck. 2021;43:1331-44. DOI: https://doi.org/10.1002/hed.26572

Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, et al. 2023 European Thyroid Association clinical practice guidelines for thyroid nodule management. Eur Thyroid J. 2023;12:e230067. DOI: https://doi.org/10.1530/ETJ-23-0067

Published

2026-05-04

How to Cite

1.
Caldeira M, Alonso C, Branco A, Mendes T, Soares P. Retropharyngeal Metastasis: A Rare and Frequently Aggressive Presentation of Papillary Thyroid Carcinoma. Acta Med Port [Internet]. 2026 May 4 [cited 2026 Jun. 5];39(5):323-5. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/24464

Issue

Section

Editorial