Prevalence of arterial hypertension in Cushing's syndrome.

Authors

  • D Rodrigues Serviço de Endocrinologia, Diabetes e Metabolismo, Hospitais da Universidade de Coimbra.
  • L Barros
  • L Ruas
  • L Gomes
  • E Geraldes
  • M C Ruas

DOI:

https://doi.org/10.20344/amp.2513

Abstract

To determine the prevalence of hypertension (HT) in patients with Cushing's syndrome.We studied 23 patients with Cushing's syndrome, 17 women (mean +/- SD age = 42.8 +/- 15.6 years) and 6 men (mean +/- SD age = 34.8 +/- 10.2 years). The etiologies were: 16-Cushing's disease, 3-suprarenal adenoma, 2-suprarenal carcinoma and 2-iatrogenic. Blood pressure (BP) was measured at least three times and we consider hypertension when systolic BP > or = 140 mmHg and/or diastolic BP > or = 90 mmHg.The prevalence of HT, at diagnosis, was 73.9% (64.7% in women and 100% in men) and the mean BP was 163 +/- 25/100 +/- 16 mmHg (158 +/- 26/97 +/- 15 mmHg in women and 182 +/- 5/114 +/- 10 mmHg in men). From the 16 patients with Cushing's disease, 13 (81%) had HT; all the patients (n = 3) with suprarenal adenoma had HT; none with suprarenal carcinoma (n = 2) had HT and only 1 of the 2 patients with iatrogenic Cushing's syndrome had HT. After treatment, 14 patients entered remission, 6 persisted with active disease and 1 was missed during the follow-up. In the group of patients that entered remission, the prevalence of HT at diagnosis was 78.5% (n = 11), 57.1% (n = 8) being after treatment.In this study, we found a high prevalence of HT at diagnosis (73.9%). After treatment and in the patients that entered remission, the prevalence of HT remained high (78.5% vs 57.1%). The high prevalence of HT in Cushing's syndrome, suggests its importance as a morbidity factor and also as an important diagnostic indicator, when present.

Downloads

Download data is not yet available.

How to Cite

1.
Rodrigues D, Barros L, Ruas L, Gomes L, Geraldes E, Ruas MC. Prevalence of arterial hypertension in Cushing’s syndrome. Acta Med Port [Internet]. 1997 Dec. 1 [cited 2024 Nov. 5];10(11):785-7. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/2513

Issue

Section

Arquivo Histórico