The rare metastasis of osteosarcoma of a long bone associated with von Recklinghausen's neurofibromatosis.

M M Ferreira, H Mansinho, A Fernandes, F S Pereira, J A Assis e Santos


We report a case of femoral osteosarcoma with brain metastases in a female patient with longstanding von Recklinghausen disease. Osteosarcoma of a long bone has not yet, to our best knowledge, been reported in association with type I Neurofibromatosis. Central nervous system metastases occur very rarely in osteosarcoma.

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