Pure autonomic failure.

Authors

  • J L Ducla-Soares Serviço de Medicina III, Hospital de Santa Maria, Lisboa.
  • A S Guerreiro
  • P Póvoa
  • E Alvares
  • L Guerreiro
  • F Carrilho
  • M Santos
  • J Figueirinhas
  • M Carvalho

DOI:

https://doi.org/10.20344/amp.3154

Abstract

We present the case of a 64-year-old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomia and xerophthalmia, dysuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowing the diagnosis of denervation hypersensitivity. The diagnosis of pure autonomic failure was made. Therapy with 9 alpha fludrocortisone and metoclopramide was initiated with marked and sustained symptomatic effect.

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How to Cite

1.
Ducla-Soares JL, Guerreiro AS, Póvoa P, Alvares E, Guerreiro L, Carrilho F, Santos M, Figueirinhas J, Carvalho M. Pure autonomic failure. Acta Med Port [Internet]. 1993 Nov. 30 [cited 2024 Mar. 29];6(11):533-7. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/3154

Issue

Section

Arquivo Histórico