Blood transfusion in sickle cell disease.

D E Santo, F Graça

Abstract


Sickle cell disease is a genetic disorder characterized by the presence of hemoglobin S. This hemoglobin has a low affinity for oxygen, allowing a good oxygenation of tissues with low levels of hemoglobin. Therefore, blood transfusions are not necessary to correct basal anemia, but are indispensable in the treatment and prevention of some complications. Detailed indications for blood transfusions are presented, as well as the different types of transfusion usually performed: simple, exchange and hypertransfusion. Finally, reference is made to the preferable blood components to be used, complications related with transfusion, the preventive measures to be taken and the need for a patient's transfusion record.

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