Epidermolysis bullosa and dermo-epidermic junction. Clinico-pathologic correlation.

F G Rodrigo, A J Mayer-da-Silva


Epidermolysis bullosa encompasses a group of hereditary diseases clinically and pathologically characteristic. In this review the grouping criteria commonly accepted for their classification are described. The cleavage phenomena observed in these diseases are analysed in accordance with the concept of a skin area including dermal and epidermal interrelated structures--the dermo-epidermal junction zone. Finally in the most expressive forms the clinical manifestations, diagnosis and treatment are reviewed.

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