Essential thrombocythemia. Therapy with interferon alfa.

L Lebre, A Sousa, J Sampaio, L Novais, E Júnior, R Coelho, J Simões


A clinical case of essential thrombocythaemia is presented to demonstrate good therapeutic response to subcutaneous Alpha-2b Interferon in a dosage of 3 x 10(6) units, three times a week. Based on this case and on a literature research we propose that Alpha-2b Interferon is a legitimate alternative to alkylating agents or radioactive phosphorus (32P), showing identical efficacy and less Leukemogen effect.

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