A study of the possible relationship of serum dopamine-beta-hydroxylase activity with diabetic neuropathy.

M. Silva Azevedo; F. Fernandes; M. L. Sales Luís; P. Lisboa; C. Manso

doi:10.20344/amp.4397

A study of the possible relationship of serum dopamine-beta-hydroxylase activity with diabetic neuropathy.

Authors

M. Silva Azevedo Instituto de Química Fisiológica. Faculdade de Medicina and Department of Diabetes, Hospital de Santa Maria. Lisbon. Portugal.
F. Fernandes
M. L. Sales Luís Instituto de Quimica Fisiologica and Centro de Estudos Egas Moniz, Faculdade de Medicina and Department of Diabetes, Hospital de Santa Maria. Lisbon. Portugal.
P. Lisboa Instituto de Quimica Fisiologica and Centro de Estudos Egas Moniz, Faculdade de Medicina and Department of Diabetes, Hospital de Santa Maria. Li~bon. Portugal.
C. Manso Instituto de Quimica Fisiologica and Centro de Estudos Egas Moniz, Faculdade de Medicina and Department of Diabetes, Hospital de Santa Maria. Lisbon. Portugal.

DOI:

https://doi.org/10.20344/amp.4397

Abstract

Serum DBH activity in a normal population of 58 individuals shows a gaussian distribution, on the opposite to what happens in a population of 100 diabetics. These two populations also differ statistically by the analysis of variance. However it was round that it is not possible to correlate serum DBH neither with insulin administration, type of diabetes, duration of disease, nor with the severity of the involvement of the peripheral nerves. It is hypothesized that the variation of DBH in diabetics may have a multifactorial cause, resulting from several metabolic and circulatory alterations that accompany the disease.

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How to Cite

Azevedo MS, Fernandes F, Luís MLS, Lisboa P, Manso C. A study of the possible relationship of serum dopamine-beta-hydroxylase activity with diabetic neuropathy. Acta Med Port [Internet]. 1979 Oct. 30 [cited 2024 Nov. 26];1(5):561-7. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/4397

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Issue

Vol. 1 No. 5 (1979): Setembro-Outubro

Section

Arquivo Histórico

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