Comparing the Application of Hema-Obs RSS to 250 Pregnancies from Obstetrics/Hematology Consultation in Centro Hospitalar São João, Portugal with the Application of Galit Sarig RSS to 90 Pregnancies from Rambam Health Care Campus, Israel

Authors

  • Ana Salselas Serviço de Imuno-Hemoterapia. Centro Hospitalar de S. João. Porto. Portugal.
  • Inês Pestana Serviço de Ginecologia e Obstetrícia. Centro Hospitalar de S. João. Porto. Portugal.
  • Francisco Bischoff Serviço de Imuno-Hemoterapia. Centro Hospitalar de S. João. Porto. Portugal.
  • Mariana Guimarães Serviço de Ginecologia e Obstetrícia. Centro Hospitalar de S. João. Porto. Portugal.
  • Joaquim Aguiar Andrade Serviço de Hematologia Clínica. Centro Hospitalar de S. João. Porto. Portugal.

DOI:

https://doi.org/10.20344/amp.5200

Keywords:

Comparative Study, Israel, Portugal, Pregnancy, Risk Assessment comparative study, Thrombophilia.

Abstract

Introduction: Pregnant women with thromboembolic diseases, previous thrombotic episodes or thrombophilia family history were supervised in a multidisciplinary Obstetrics/ Hematology consultation in Centro Hospitalar São João EPE, Porto, Portugal. For the evaluation and medication of these women, a risk stratification scale was used.
Purposes: The aim of this study was to validate a Risk Stratification Scale and thromboprophylaxis protocol by means of comparing it with a similar scale, developed and published by Sarig.
Material and Methods: We have compared: The distribution, by risk groups, obtained through the application of the two scales on pregnant women followed at Centro Hospitalar São João, Porto, Portugal, consultation; the sensibility and specificity for each one of the scales (DeLong scale, applied to Receiver Operating Characteristic) curves; the outcomes in pregnancies followed in Hospital São João, Porto, Portugal
Results: According to our Hema-Obs risk stratification scale, 29% were allocated to low-risk, 47% to high-risk and 24% to very-high-risk groups. According to Galit Sarig risk stratification scale, 24% were considered low-risk, 53% moderate, 16% high-risk and 7% as very high-risk group. In our study we observed 9% of spontaneous abortions, in comparison with 18% in the Galit Sarig cohort. From the application of Receiver Operating Characteristic curve to both risk stratification scales, the results of the calculated areas were 58,8% to our Hema-Obs risk stratification scale and 38,7% to Galit Sarig risk stratification scale, with a Delong test significancie of p = 0.0006.
Conclusions: We concluded that Hema-Obs risk stratification scale is an effective support for clinical monitoring of therapeutic strategies.

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Published

2015-04-30

How to Cite

1.
Salselas A, Pestana I, Bischoff F, Guimarães M, Andrade JA. Comparing the Application of Hema-Obs RSS to 250 Pregnancies from Obstetrics/Hematology Consultation in Centro Hospitalar São João, Portugal with the Application of Galit Sarig RSS to 90 Pregnancies from Rambam Health Care Campus, Israel. Acta Med Port [Internet]. 2015 Apr. 30 [cited 2024 Mar. 28];28(2):189-93. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/5200