Guidelines for prevention of febrile neutropenia.

Authors

  • Sérgio Barroso Serviço de Oncologia, Hospital do Espírito Santo, Evora.
  • Margarida Damasceno
  • José Dinis
  • Helena Gervásio
  • Ricardo da Luz
  • J L Passos-Coelho
  • Anabela Sá
  • Luís Costa
  • Helena Rodrigues
  • Sofia Andrade
  • Ana Macedo
  • Inês Moital

DOI:

https://doi.org/10.20344/amp.767

Abstract

Neutropenia and febrile neutropenia are common consequences of some cytotoxic chemotherapy regimens. This situation leads to modifications of the therapeutic regimen, conducting to either dose reduction or cycle delays. Granulocyte colony stimulating factors are commonly used to minimize chemotherapy cytotoxic effect on the granulocytic series. The objective of this study is to assess the available evidence in what concerns the efficacy and safety of granulocyte colony stimulating factors, in several settings of their use. An extensive bibliographic review was performed, including clinical trials, observational studies, systematic reviews, and international guidelines for neutropenia prophylaxis, which aims to establish recommendations on their use, in adequacy to the National reality.

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How to Cite

1.
Barroso S, Damasceno M, Dinis J, Gervásio H, da Luz R, Passos-Coelho JL, Sá A, Costa L, Rodrigues H, Andrade S, Macedo A, Moital I. Guidelines for prevention of febrile neutropenia. Acta Med Port [Internet]. 2008 Apr. 18 [cited 2024 Mar. 29];21(1):7-19. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/767

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Section

Arquivo Histórico