Alina Osuna, Adelino Carragoso, Ana Lemos, Maria Luísa Mocho, Orlando Gaspar


Cryptococcus neoformans infection is an opportunistic infection affecting mainly patients lacking cell mediated immunity whose incidence has dramatically risen with the advent of HIV infection. This infection has rarely been reported in patients with humoral immunity deficiencies. We report two patients with Cryptococcus neoformans infection with a fatal outcome: a man with disseminated criptococcosis leading to the diagnosis of AIDS; and a woman with stage III- B K light chains multiple myeloma presenting with meningitis to both Cryptococcus neoformans and Listeria monocytogenes.

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