Syndrome of Irreversible Lithium-Effectuated NeuroToxicity

Authors

  • Ana Luísa Silva Serviço de Medicina Interna. Centro Hospitalar de São João. Porto. Portugal.
  • Carolina Ourique Serviço de Medicina Interna. Centro Hospitalar de São João. Porto. Portugal.
  • Filipe Martins Serviço de Medicina Interna. Centro Hospitalar de São João. Porto. Portugal.
  • Fernando Friões Unidade de Cuidados Intermédios de Medicina. Centro Hospitalar de São João. Porto. Portugal.

DOI:

https://doi.org/10.20344/amp.7907

Keywords:

Lithium/adverse effects, Neurotoxicity Syndromes/etiology

Abstract

Lithium has a narrow therapeutic window. Frequent monitoring of both serum levels and clinical signs of toxicity is warranted because toxicity may be present even when concentrations are within the therapeutic range. We report the case of a man with lithium poisoning, with persistent neurologic signs and symptoms even after removal of lithium from circulation – a diagnosis of syndrome of irreversible lithium-effectuated neurotoxicity (SILENT) was made.

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Published

2017-02-27

How to Cite

1.
Silva AL, Ourique C, Martins F, Friões F. Syndrome of Irreversible Lithium-Effectuated NeuroToxicity. Acta Med Port [Internet]. 2017 Feb. 27 [cited 2024 Nov. 5];30(2):151-3. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/7907

Issue

Section

Case Report