Nifedipine antihypertensive treatment effects in pre-eclampsia.

Alex R De Souza, Melania R Amorim, Aurélio R Costa


Literature analysis has been controversial about pre-eclampsia. It is known that not pregnant patients should be treated due cardiovascular benefits. However, the real benefits of antihypertensive treatment in pre-eclampsia were not demonstrated. Yet, there are many drugs that can be used for antihypertensive treatment in pregnancy. Calcium cannel blockers, particularly nifedipine, are used as a second line treatment. There are just a few evidences about nifedipine treatment in hypertension during pregnancy. Recently, researches were performed to evaluate the effects of nifedipine on maternal-fetal binomial, more safety, efficacy, and effectiveness were found using it. This literature review concludes that hypertension treatment only must be done in severe cases and emergency hypertensive. Therefore nifedipine can be used in antihypertensive treatment during pregnancy without serious complications.

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