Linfohistiocitose Hemofagocítica Secundária a Infeção por Epstein-Barr: Raridade e Gravidade num Adulto Imunocompetente

Andreia Sofia Costa; Anusca Paixão; Henrique Santos; Fernando Salvador

doi:10.20344/amp.9474

Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis: Rarity and Severity in an Immunocompetent Adult

Authors

Andreia Sofia Costa Serviço de Medicina Interna. Centro Hospitalar de Trás-os-Montes e Alto Douro. Vila Real.
Anusca Paixão Serviço de Medicina Interna. Centro Hospitalar de Trás-os-Montes e Alto Douro. Vila Real.
Henrique Santos Serviço de Medicina Intensiva. Centro Hospitalar de Trás-os-Montes e Alto Douro. Vila Real.
Fernando Salvador Serviço de Medicina Interna. Centro Hospitalar de Trás-os-Montes e Alto Douro. Vila Real.

DOI:

https://doi.org/10.20344/amp.9474

Keywords:

Disseminated Intravascular Coagulation, Epstein-Barr Virus Infections, Immunocompromised Host, Lymphohistiocytosis, Hemophagocytic, Shock, Septic

Abstract

Hemophagocytic lymphohistiocytosis is a rare, aggressive and life-threatening syndrome, characterized by an excessive immune activation. It is triggered by multiple stimuli, with infections having an important role. The most common infectious trigger is viral infection, particularly by Epstein-Barr virus. Coagulation disorders are common in hemophagocytic lymphohistiocytosis and disseminated intravascular coagulation can be present in severe cases. We report a clinical case of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis, complicated with disseminated intravascular coagulation which evolved favorably with only supportive therapy and without specific treatment.

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Published

2019-02-01

How to Cite

Costa AS, Paixão A, Santos H, Salvador F. Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis: Rarity and Severity in an Immunocompetent Adult. Acta Med Port [Internet]. 2019 Feb. 1 [cited 2024 Dec. 26];32(1):78-80. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/9474

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Issue

Vol. 32 No. 1 (2019): January

Section

Case Report

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