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Thyroid associated orbitopathy.


 
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1. Title Title of document Thyroid associated orbitopathy.
 
2. Creator Author's name, affiliation, country Marta Alves; Serviço de Endocrinologia, Hospital de S. João, Porto, Portugal.; Portugal
 
2. Creator Author's name, affiliation, country Celestino Neves; Portugal
 
2. Creator Author's name, affiliation, country Davide Carvalho; Portugal
 
2. Creator Author's name, affiliation, country José Luís Medina; Portugal
 
3. Subject Discipline(s)
 
3. Subject Keyword(s)
 
4. Description Abstract Thyroid associated orbitopathy is a clinical entity with pathogenic mechanisms not fully understood, and appears in about 90% of cases in association with hyperthyroidism of Graves' disease. Its approach involves the recognition of typical features and the exclusion of other diseases in the less common presentations. The treatment is conditioned by the determination of the activity and severity of the disease. The restoration of the euthyroid state and avoiding of hypothyroidism are essential in mitigating the progression of orbitopathy. Glucocorticoid intravenous therapy is the treatment of choice in the active phase and surgical treatment in the inactive phase. Radiotherapy and cyclosporine in combination with corticosteroids are alternatives when monotherapy is insufficient in the active phase. Treatment should be instituted in specialized centers, with ophthalmologists and endocrinologists acting in synergy to avoid consequences of delays in intervention and in optimizing therapy.
 
5. Publisher Organizing agency, location Ordem dos Médicos
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2012-06-20
 
8. Type Status & genre article
 
8. Type Type
 
9. Format File format PDF (Português)
 
10. Identifier Uniform Resource Identifier https://actamedicaportuguesa.com:443/revista/index.php/amp/article/view/1410
 
10. Identifier Digital Object Identifier (DOI) http://dx.doi.org/10.20344/amp.1410
 
11. Source Title; vol., no. (year) Acta Médica Portuguesa; Vol 24, No 6 (2011): Novembro-Dezembro
 
12. Language English=en
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c)