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PKP Metadata Items |
Metadata for this Document |
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| 1. |
Title |
Title of document |
Aggressive NK/T cell leukemia/lymphoma associated with EBV. |
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| 2. |
Creator |
Author's name, affiliation, country |
Jamira Sousa; Serviço de Medicina Interna, Hospitais da Universidade de Coimbra, Coimbra, Portugal.; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
Lourdes Cabezuelo; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
Sérgio Almeida; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
Carlos Filipe; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
Adélia Simão; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
Armando Carvalho; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
J Nascimento Costa; Portugal |
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| 3. |
Subject |
Discipline(s) |
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| 3. |
Subject |
Keyword(s) |
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| 4. |
Description |
Abstract |
The authors describe an unusual case of a young man presenting with fever, asthenia, anorexia and jaundice, associated to hepatosplenomegaly, evolving rapidly to multiorganic failure. Final diagnosis revealed an aggressive NK cell leukemia/lymphoma associated to the Epstein-Barr virus (EBV). The diagnosis, suggested clinically and after bone marrow immunophenotyping, was confirmed by morphologic and immunohistochemical findings on the post-mortem hepatic and splenic biopsy .The tumor cells were positive for CD3 and cytotoxic molecules, TIA, granzyme B and perforin. The herein reported case is a rare clinical entity, only recently recognized and with a difficult early diagnosis. We emphasize the necessity to exclude a Natural Killer cell malignancy in cases with identical characteristics. |
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| 5. |
Publisher |
Organizing agency, location |
Ordem dos Médicos |
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| 6. |
Contributor |
Sponsor(s) |
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| 7. |
Date |
(YYYY-MM-DD) |
2011-12-30
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| 8. |
Type |
Status & genre |
article |
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| 8. |
Type |
Type |
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| 9. |
Format |
File format |
PDF (Português) |
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| 10. |
Identifier |
Uniform Resource Identifier |
https://actamedicaportuguesa.com/revista/index.php/amp/article/view/1547 |
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| 10. |
Identifier |
Digital Object Identifier (DOI) |
http://dx.doi.org/10.20344/amp.1547 |
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| 11. |
Source |
Title; vol., no. (year) |
Acta Médica Portuguesa; Vol 24 (2011): Suplemento 3 |
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| 12. |
Language |
English=en |
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| 14. |
Coverage |
Geo-spatial location, chronological period, research sample (gender, age, etc.) |
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| 15. |
Rights |
Copyright and permissions |
Copyright (c)
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