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PKP Metadata Items |
Metadata for this Document |
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| 1. |
Title |
Title of document |
Acute megaloblastic anemia caused by inhalation of nitrous oxide in a patient with multiple autoimmune pathology. |
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| 2. |
Creator |
Author's name, affiliation, country |
L Barbosa; Serviço de Medicina, Hospital de S. José, Lisboa.; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
I Leal; Portugal |
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Creator |
Author's name, affiliation, country |
A T Timóteo; Portugal |
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| 2. |
Creator |
Author's name, affiliation, country |
T Matias; Portugal |
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| 3. |
Subject |
Discipline(s) |
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| 3. |
Subject |
Keyword(s) |
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| 4. |
Description |
Abstract |
Although megaloblastic anemias are generally regarded as chronic conditions of insidious appearance, a megaloblastic state can arise over the course of only a few days due to acute folate or vitamin B12 deficiency. One of the most common causes, though seldom reported, is the nitrous oxide (N02) action in tissue. In fact N02, a volatile substance commonly used in anaesthesia, destroys methylcobalamin, leading to the rapid development of a megaloblastic haematopoiesis. This phenomenon may occur in patients without previous vitamin B12 deficit, but is more frequent and severe when there is a pre-existent deficiency state. A case report is described of a patient with femoral fracture who developed acute anemia after surgery and a latent pernicious anemia was revealed upon investigation. |
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| 5. |
Publisher |
Organizing agency, location |
Ordem dos Médicos |
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| 6. |
Contributor |
Sponsor(s) |
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| 7. |
Date |
(YYYY-MM-DD) |
2000-12-30
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| 8. |
Type |
Status & genre |
article |
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| 8. |
Type |
Type |
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| 9. |
Format |
File format |
PDF (Português) |
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| 10. |
Identifier |
Uniform Resource Identifier |
https://actamedicaportuguesa.com:443/revista/index.php/amp/article/view/1798 |
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| 10. |
Identifier |
Digital Object Identifier (DOI) |
http://dx.doi.org/10.20344/amp.1798 |
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| 11. |
Source |
Title; vol., no. (year) |
Acta Médica Portuguesa; Vol 13, No 5-6 (2000): Setembro-Dezembro |
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| 12. |
Language |
English=en |
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| 14. |
Coverage |
Geo-spatial location, chronological period, research sample (gender, age, etc.) |
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| 15. |
Rights |
Copyright and permissions |
Copyright (c)
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