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deficiency of growth hormone in children. Re-evaluation after therapeutic completion.


 
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1. Title Title of document deficiency of growth hormone in children. Re-evaluation after therapeutic completion.
 
2. Creator Author's name, affiliation, country T Martins; Serviço de Endocrinologia, Diabetes e Metabolismo, Hospitais da Universidade de Coimbra, Coimbra.; Portugal
 
2. Creator Author's name, affiliation, country M Bastos; Portugal
 
2. Creator Author's name, affiliation, country P Leitão; Portugal
 
2. Creator Author's name, affiliation, country L Barros; Portugal
 
2. Creator Author's name, affiliation, country L Ruas; Portugal
 
2. Creator Author's name, affiliation, country C Batista; Portugal
 
2. Creator Author's name, affiliation, country S Paiva; Portugal
 
2. Creator Author's name, affiliation, country M Carvalheiro; Portugal
 
2. Creator Author's name, affiliation, country M M Ruas; Portugal
 
3. Subject Discipline(s)
 
3. Subject Keyword(s)
 
4. Description Abstract To assess GH secretion in young adults treated with GH replacement therapy in childhood.From the 38 patients who concluded treatment with GH, we studied 20 (52.6%), 9 girls and 11 boys. Thirteen had Growth Hormone Deficiency (GHD)-65%, while 7 had Multiple Pituitary Hormone Deficiency (MPHD)-35%. The patients were retested within 6 months to 6 years after completing GH therapy. The mean age (+/- SD) at retesting was 18.1 +/- 2.6 years for those with GHD and 20.8 +/- 2.8 for those with MPHD. At reassessment we performed two provocative tests: insulin tolerance test (ITT) and clonidine test.Seven of the 20 patients retested, retained GH deficiency. Of the 13 patients with GHD, only one maintained the deficiency, while of the 7 patients with MPHD, 6 maintained the deficiency.Young adults with GH deficiency treated with this hormone should be retested in order to identify those who are truly GH insufficient adults and may benefit from replacement therapy.
 
5. Publisher Organizing agency, location Ordem dos Médicos
 
6. Contributor Sponsor(s)
 
7. Date (YYYY-MM-DD) 2000-12-30
 
8. Type Status & genre article
 
8. Type Type
 
9. Format File format PDF (Português)
 
10. Identifier Uniform Resource Identifier https://actamedicaportuguesa.com:443/revista/index.php/amp/article/view/1802
 
10. Identifier Digital Object Identifier (DOI) http://dx.doi.org/10.20344/amp.1802
 
11. Source Title; vol., no. (year) Acta Médica Portuguesa; Vol 13, No 5-6 (2000): Setembro-Dezembro
 
12. Language English=en
 
14. Coverage Geo-spatial location, chronological period, research sample (gender, age, etc.)
 
15. Rights Copyright and permissions Copyright (c)