The Genetic Psychosocial Risk Instrument (GPRI): A Validation Study for European Portuguese

Pedro Gomes; Tiago Ferreira; Paula Mena Matos; Eunice Silva; João Silva; Mary Jane Esplen; Célia M. D. Sales

doi:10.20344/amp.16497

Autores

Pedro Gomes Cancer Genetics Group. Research Centre of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network). Portuguese Oncology Institute of Porto. Porto Comprehensive Cancer Centre. Porto. Centre for Psychology. Faculty of Psychology and Education Sciences. University of Porto. Porto. https://orcid.org/0000-0001-9477-4434
Tiago Ferreira Centre for Psychology. Faculty of Psychology and Education Sciences. University of Porto. Porto. https://orcid.org/0000-0002-2884-2547
Paula Mena Matos Centre for Psychology. Faculty of Psychology and Education Sciences. University of Porto. Porto. https://orcid.org/0000-0001-5763-8070
Eunice Silva Cancer Genetics Group. Research Centre of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network). Portuguese Oncology Institute of Porto. Porto Comprehensive Cancer Centre. Porto.Psychology Department. Portuguese Oncology Institute of Porto. Porto. https://orcid.org/0000-0002-3403-6058
João Silva Medical Genetics Department. Portuguese Oncology Institute of Porto. Porto. https://orcid.org/0000-0002-6041-1763
Mary Jane Esplen Department of Psychiatry. Faculty of Medicine. University of Toronto. Toronto.
Célia M. D. Sales Centre for Psychology. Faculty of Psychology and Education Sciences. University of Porto. Porto. https://orcid.org/0000-0002-2586-8469

DOI:

https://doi.org/10.20344/amp.16497

Palavras-chave:

Aconselhamento Genético, Estudo de Validação, Psico-Oncologia, Psicometria, Síndromes Neoplásicas Hereditárias, Teste Genético, Tradução

Resumo

Introdução: A literatura tem apontado a necessidade de instrumentos de rastreio de risco psicossocial desenvolvidos especificamente para o contexto do teste genético. No entanto, de acordo com o nosso melhor conhecimento, não existe nenhum instrumento com estas características que esteja validado para a língua portuguesa. Este artigo apresenta o processo de tradução, adaptação e validação do Instrumento de Risco Psicossocial Genético numa amostra de 207 utentes convidados à realização de testes genéticos no contexto de risco de cancro hereditário.
Material e Métodos: Os participantes são maioritariamente do sexo feminino (84,06%), com média de idade de 40,08 (DP = 12,89) e foram recrutados no Instituto Português de Oncologia do Porto. Foi realizada uma análise fatorial confirmatória para estudar a estrutura fatorial do Instrumento de Risco Genético Psicossocial. A validade convergente foi avaliada com a Escala de Impacto de Eventos, a Escala da Avaliação de Rotina de Resultado Clínico - Medida de Resultado e a Escala de Ansiedade e Depressão Hospitalar.
Resultados: Confirmou-se um modelo composto pelos fatores ‘Impacto Interno do Teste Genético’, ‘Impacto Externo do Teste Genético’ e ‘Histórico de Preocupações com a Saúde Mental’. Estes fatores apresentaram boa consistência interna, validade convergente e discriminante. O fator ‘Perda Pessoal para o Cancro’ proposto nas versões Canadiana e Francesa não convergiu. Propomos excluir este fator da versão portuguesa da escala.
Conclusão: A versão portuguesa do Instrumento de Risco Genético Psicossocial é um instrumento confiável e válido, embora seja necessária mais investigação para que seja integrado efetivamente na prática de rotina.

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