What is the Benefit of Salt Reduction on Blood Pressure? Assessment of the Cochrane Review “Effect of longer-term modest salt reduction on blood pressure. He FJ, Li J, Macgregor GA. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937.

Daniel Caldeira, António Vaz-Carneiro, João Costa

Abstract


In the present article we evaluate and comment the systematic review from Cochrane Collaboration “Effect of longer-term modest salt reduction on blood pressure. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004937”.
Clinical Question: What is the impact of long-term (≥ 4 weeks) modest salt (sodium chloride) reduction on arterial blood pressure?
Conclusions: This systematic review concluded that a moderate reduction in salt intake (mean reduction -4.4 g per day) resulted in statistically significant decreases in blood pressure (BP) that may be helpful in normotensive (-2.42 mmHg systolic BP; -1.00 mmHg diastolic BP) and hypertensive patients (-5.39 mmHg systolic BP; -2.82 mmHg diastolic BP). There were slight increases in physiological plasma renin activity, aldosterone and norepinephrine, without significant changes in lipid profile.

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