Monoclonal Gammopathies of Indetermined Significance: Diagnosis and Clinical Follow-up Guidelines

Joana Parreira, Paulo Lúcio, Cristina João, Ana Macedo, Ana Bela Sarmento, Catarina Geraldes, Cristina Gonçalves, Graça Esteves


The Portuguese group of multiple myeloma of the Portuguese Society of Hematology proposes a national protocol for diagnosis and clinical follow-up of monoclonal gammopathies. The proposed protocol aims to standardize clinical management of monoclonal gammopathies. Furthermore, it would also define the major risk factors for progression to Multiple Myeloma that require a precocious close articulation between general practitioners and a Hematology Clinic.

Keywords: Monoclonal Gammopathy of Undetermined Significance; Prognosis; Disease Progression; Long-Term Care; Portugal.

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