Analysis of the Cochrane Review: Chromoscopy Versus Conventional Endoscopy for the Detection of Polyps in the Colon and Rectum. Cochrane Database Syst Rev. 2016;4:CD006439

Authors

  • Diogo Libânio Serviço de Gastrenterologia. Instituto Português de Oncologia do Porto. Porto. Portugal. CINTESIS – Center for Health Technology and Services Research. Faculdade de Medicina. Universidade do Porto. Porto. Portugal.
  • Luís Filipe Azevedo CINTESIS – Center for Health Technology and Services Research. Faculdade de Medicina. Universidade do Porto. Porto. Portugal. CIDES – Departamento de Ciências da Informação e da Decisão em Saúde. Faculdade de Medicina. Universidade do Porto. Porto. Portugal. Cochrane Portugal – Unidade do Porto. Centro Cochrane Iberoamericano. Porto. Portugal.

DOI:

https://doi.org/10.20344/amp.7968

Keywords:

Colonic Polyps/diagnosis, Colonoscopy, Indicators and Reagents, Indigo Carmine, Intestinal Polyps/diagnosis, Precancerous Conditions/diagnosis, Randomized Controlled Trials as Topic, Rectal Diseases/diagnosis.

Abstract

Although colonoscopy is considered the most accurate test for the investigation of colorectal polyps, lesions ≤ 10 mm may be missed in approximately 10%. Chromoscopy may increase the detection of colorectal polyps. A systematic review and meta-analysis was performed to investigate the benefit of cromoscopy in colorectal polyps detection. Seven randomized controlled trials were included (incuding 2,727 participants) comparing polyp detection (both neoplastic and non- neoplastic polyps) in patients submitted to conventional colonoscopy or colonoscopy with chromoscopy. Chromoscopy was associated with a significant improvement in all detection endpoints (number of polyps, number of neoplastic polyps, number of diminutive polyps, number of neoplastic diminutive polyps, proportion of patients with at least one polyp and proportion of patients with at least one neoplastic polyp). However, when highdefinition colonoscopes were used in the control group, chromoscopy benefit does not seem to be significant. Besides, routine use of chromoscopy may have implications in the accessibility of colonoscopy and in the effectiveness of screening programs. Moreover, the benefit of chromoscopy in the era of high-definition colonoscopy is questionable.

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Author Biography

Luís Filipe Azevedo, CINTESIS – Center for Health Technology and Services Research. Faculdade de Medicina. Universidade do Porto. Porto. Portugal. CIDES – Departamento de Ciências da Informação e da Decisão em Saúde. Faculdade de Medicina. Universidade do Porto. Porto. Portugal. Cochrane Portugal – Unidade do Porto. Centro Cochrane Iberoamericano. Porto. Portugal.

Provas de Aptidão Pedagógica e Capacidade Científica Instituição: Faculdade de Medicina da Universidade do Porto Data de conclusão: 2008/5/9 Pós-Graduação em Probabilidade e Estatística Instituição: Faculdade de Ciências da Universidade de Lisboa Data de conclusão: 2006 Licenciatura em Medicina Instituição: Faculdade de Medicina da Universidade do Porto Data de conclusão: 2001

Published

2016-10-31

How to Cite

1.
Libânio D, Azevedo LF. Analysis of the Cochrane Review: Chromoscopy Versus Conventional Endoscopy for the Detection of Polyps in the Colon and Rectum. Cochrane Database Syst Rev. 2016;4:CD006439. Acta Med Port [Internet]. 2016 Oct. 31 [cited 2024 Mar. 19];29(10):583-6. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/7968

Issue

Section

Cochrane Corner