Polysaccharide of Escherichia coli in the Prevention of Recurrent Urinary Tract Infection: An Evidence-Based Review

Authors

  • Manuel Tinoco Unidade Saúde Familiar Casa dos Pescadores. Póvoa de Varzim.
  • Mélody Santos Unidade Saúde Familiar Casa dos Pescadores. Póvoa de Varzim.
  • Conceição Reitor Unidade Saúde Familiar Casa dos Pescadores. Póvoa de Varzim.
  • Andreia Rodrigues Unidade Saúde Familiar Casa dos Pescadores. Póvoa de Varzim.
  • João Monteiro Unidade Saúde Familiar Casa dos Pescadores. Póvoa de Varzim.

DOI:

https://doi.org/10.20344/amp.9367

Keywords:

Adjuvants, Immunologic/therapeutic use, Escherichia coli Infections, Urinary Tract Infections, Uropathogenic Escherichia coli

Abstract

Introduction: Recurrent urinary tract infection is frequent and it is related to morbidity, costs and growing antibiotic resistance. OM 8930 vaccine is composed by Escherichia coli polysaccharide and it is a possible prophylactic measure, but there is doubt as to its effectiveness.
Material and Methods: We performed a systematic review in evidence-based medicine databases with rigorous bibliography selection.
Results: We found an effective decrease of recurrences in test groups.
Discussion: We recommend the administration of the vaccine as prophylaxis of recurrent cystitis.
Conclusion: The vaccine has impact on the recurrent cystitis relapse rate. We suggest that more studies be carried out to evaluate the vaccine cost-benefit and its effectiveness in complicated urinary infections.

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Published

2018-03-29

How to Cite

1.
Tinoco M, Santos M, Reitor C, Rodrigues A, Monteiro J. Polysaccharide of Escherichia coli in the Prevention of Recurrent Urinary Tract Infection: An Evidence-Based Review. Acta Med Port [Internet]. 2018 Mar. 29 [cited 2024 Mar. 29];31(3):165-9. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/9367

Issue

Section

Review Articles