Recurrent Bacteremia after Cyanoacrylate Sclerotherapy of Ectopic Duodenal Varices

Authors

DOI:

https://doi.org/10.20344/amp.19444

Keywords:

Bacteremia/etiology, Enbucrilate/adverse effects, Esophageal and Gastric Varices/therapy, Gastrointestinal Hemorrhage, Sclerotherapy/ adverse effects

Abstract

Sclerotherapy with N-butyl-2-cyanoacrylate is the first-line endoscopic approach for gastric and ectopic variceal bleeding, but it can be associated with local or systemic complications. Episodes of transient bacteremia after the procedure are frequent, but documented cases of recurrent bacteremia are rare. The authors report a 47-year-old female patient with liver cirrhosis who underwent duodenal sclerotherapy with cyanoacrylate after upper gastrointestinal bleeding. Subsequently, she developed five episodes of bacteremia with unknown origin. A definitive diagnosis of recurrent bacteremia due to cyanoacrylate was only possible after an exhaustive study to exclude other infectious foci. This case highlights a rare complication in an unusual topography (ectopic varices) and with a high number of episodes of bacteremia. A multidisciplinary management was paramount due to the patient’s high surgical and anesthetic risk, comorbidities, and surgical aggressiveness.

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References

European Association for the Study of the Liver. EASL clinical practice guidelines for the management of patients with decompensated cirrhosis. J Hepatol. 2018;69:406-60. DOI: https://doi.org/10.1016/j.jhep.2018.08.009

Chen WC, Hou MC, Lin HC, Yu KW, Lee FY, Chang FY, et al. Bacteremia after endoscopic injection of N-Butyl-2-cyanoacrylate of gastric variceal bleeding. Gastrointest Endosc. 2001;54:214-8. DOI: https://doi.org/10.1067/mge.2001.116566

Al-Hillawi L, Wong T, Tritto G, Berry P. Pitfalls in histoacryl glue injection therapy for oesophageal, gastric and ectopic varices: a review. World J Gastrointest Surg. 2016;8:729-34. DOI: https://doi.org/10.4240/wjgs.v8.i11.729

Randi B, Ninomiya D, Nicodemo E, Lopes B, Cançado E, Levin A. Recurrent bacteremia after injection of N-Butyl-2-cyanoacrylate for treatment of bleeding gastric varices: a case report and review of the literature. BMC Res Notes. 2015;8:692. DOI: https://doi.org/10.1186/s13104-015-1679-6

Wright G, Matull W, Zambreanu L, O’Neill S, Smith R, O’Beirne J, et al. Recurrent bacteremia due to retained embolized glue following variceal obliteration. UTCN- Unusual cases and technical notes. Endoscopy. 2009;41:E56-7. DOI: https://doi.org/10.1055/s-2008-1077564

Martins A, Valente A, Palma R, Raimundo M, Alexandrino P, Carneiro de Moura M. Embolização pulmonar com cianoacrilato após esclerose de varizes gástricas. J Port Gastrenterol. 2006;13:291-2.

Liao SC, Ko CW, Yeh HZ, Chang CS, Yang SS, Chen GH. Successful treatment of persistente bacteremia after endoscopic injection of N-butyl-2-cyanoacrylate for gastric varices bleeding. Endoscopy. 2007;39:E176-7. DOI: https://doi.org/10.1055/s-2007-966556

Published

2023-06-30

How to Cite

1.
Martins Mendes T, Fonseca T, Pereira Anjos D. Recurrent Bacteremia after Cyanoacrylate Sclerotherapy of Ectopic Duodenal Varices. Acta Med Port [Internet]. 2023 Jun. 30 [cited 2024 Dec. 27];37(2):136-41. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/19444

Issue

Section

Case Report