Warthin’s Tumor: A Rare Case Report of a Bilateral Multifocal Parotid Tumor Associated with an Ectopic Tumor
DOI:
https://doi.org/10.20344/amp.22147Keywords:
Adenolymphoma, Parotid NeoplasmsAbstract
Warthin’s tumor is the second most common benign neoplasm of the parotid gland and frequently presents with multifocal and bilateral involvement, either synchronously or metachronously, up to 20% - 30% of cases. More rarely, extraparotid locations may also occur. This case report describes a Warthin’s tumor presenting synchronously as a multifocal bilateral parotid tumor in association with an extraparotid localization, which, according to the existing literature, appears to be a rare event. This low incidence is likely underestimated and could be explained by several reasons. Increased awareness of this potentially higher incidence may aid physicians in better evaluating and treating their patients.
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Xu W, Lu H, Zhu Y, Ruan M, Zhang C, Yang W, et al. Warthin’s tumour in oral and maxillofacial regions: an 18-year retrospective study of 1084 cases in an eastern-Chinese population. Int J Oral Maxillofac Surg. 2018;47:913-7.
Patel DK, Morton RP. Demographics of benign parotid tumours: Warthin’s tumour versus other benign salivary tumours. Acta Otolaryngol. 2016;136:83-6.
Hilton JM, Phillips JS, Hellquist HB, Premachandra DJ. Multifocal multi-site Warthin tumour. Eur Arch Otorhinolaryngol. 2008;265:1573-5.
Maiorano E, Lo Muzio L, Favia G, Piattelli A. Warthin’s tumour: a study of 78 cases with emphasis on bilaterality, multifocality and association with other malignancies. Oral Oncol. 2002;38:35-40.
Rimmer RA, Cottrill EE. Multifocal Warthin’s tumor: an uncommon presentation of bilateral cervical lymphadenopathy. Case Rep Otolaryngol. 2018;2018:3791825.
Honda K, Kashima K, Daa T, Yokoyama S, Nakayama I. Clonal analysis of the epithelial component of Warthin’s tumor. Hum Pathol. 2000;31:1377-80.
Peter Klussmann J, Wittekindt C, Florian Preuss S, Al Attab A, Schroeder U, Guntinas-Lichius O. High risk for bilateral Warthin tumor in heavy smokers-review of 185 cases. Acta Otolaryngol. 2006;126:1213-7.
Dalpa E, Gourvas V, Baritaki S, Miyakis S, Samaras V, Barbatis C, et al. High prevalence of human herpes virus 8 (hhv-8) in patients with Warthin’s tumors of the salivary gland. J Clin Virol. 2008;42:182-5.
O’Neill ID. New insights into the nature of Warthin’s tumour. J Oral Pathol Med. 2009;38:145-9.
Fíková A, Kuchař M, Kalfeřt D, Dostálová L, Balko J, Zábrodský M, et al. Experience with follow-up strategy in selected patients with Warthin tumour diagnosed by ultrasound-guided fine-needle aspiration biopsy (FNAB). Eur Arch Otorhinolaryngol. 2022;279:2049-55.
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