Parvovirus B19 in Adolescents and Adults: A Case Series of Clinical Mimicry

Authors

  • Inês Tribolet de Abreu Serviço de Dermatologia. Unidade Local de Saúde Santa Maria. Lisboa. & Faculdade de Medicina. Universidade de Lisboa. Lisboa. https://orcid.org/0009-0008-4497-9763
  • Ivânia Soares Serviço de Dermatologia. Unidade Local de Saúde Santa Maria. Lisboa. & Faculdade de Medicina. Universidade de Lisboa. Lisboa. https://orcid.org/0009-0003-0348-037X
  • Filipe Silva Monteiro Serviço de Dermatologia. Unidade Local de Saúde Santa Maria. Lisboa. & Faculdade de Medicina. Universidade de Lisboa. Lisboa. https://orcid.org/0009-0008-9950-1521
  • Gustavo Almeida-Silva Serviço de Dermatologia. Unidade Local de Saúde Santa Maria. Lisboa. & Faculdade de Medicina. Universidade de Lisboa. Lisboa. https://orcid.org/0009-0000-0669-5366
  • Paulo Filipe Serviço de Dermatologia. Unidade Local de Saúde Santa Maria. Lisboa. & Faculdade de Medicina. Universidade de Lisboa. Lisboa. & Gulbenkian Institute for Molecular Medicine. Lisboa. https://orcid.org/0000-0001-6917-527X

DOI:

https://doi.org/10.20344/amp.23424

Keywords:

Adolescent, Adult, Exanthema, Parvoviridae Infections, Parvovirus B19, Human

Abstract

Parvovirus B19 (PvB19), the etiological agent of erythema infectiosum, can manifest in diverse clinical forms. This study underscores the virus’s capacity to mimic other diseases, as illustrated by the diagnostic challenges encountered across five cases. The first three cases correspond to an overlap of papulo-purpuric gloves and socks syndrome with petechial exanthema with periflexural and periorificial distribution, the first initially diagnosed as a drug eruption, the second as scarlet fever, and the third as autoimmune thrombocytopenia. The remaining two cases correspond to leukocytoclastic vasculitis that, only after thorough investigation, were associated with Parvovirus B19 infection. This case series emphasizes the need for healthcare professionals to be alert to this important imitator and be mindful of this differential diagnosis when approaching exanthemas and vasculitis.

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References

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Published

2025-09-29

How to Cite

1.
Tribolet de Abreu I, Soares I, Silva Monteiro F, Almeida-Silva G, Filipe P. Parvovirus B19 in Adolescents and Adults: A Case Series of Clinical Mimicry. Acta Med Port [Internet]. 2025 Sep. 29 [cited 2025 Dec. 6];. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/23424

Issue

Section

Case Report