Esophageal Cancer: Surgical Strategies

Authors

  • Paulo Costa Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
  • Rui Esteves Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
  • Patrícia Lages Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.
  • Filipa Ferreira Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.

DOI:

https://doi.org/10.20344/amp.5159

Abstract

Introduction: Oesophagectomy for cancer is associated to a significant morbidity and mortality. The superiority of transthoracic vs transhiatal is still a matter of controversy. The aim of this paper is to discuss the results of a series of patients submitted to either a transthoracic or a transhiatal according to the anatomic location regarding the carina.
Material and Methods: Retrospective analysis of 52 consecutive patients, with oesophageal carcinoma, 7 female and 45 males, median age 64 [46-85] years. Location: cervical – 1; above carina - 22; below or at carina level - 19; cardia type I –10. 19 adenocarcinoma, 32 squamous cells, 1 lymphoma. Twenty patients (40%) – neo-adjuvant therapy. Thoracoabdominal approach – 3, cervico-thoracoabdominal – 20, transhiatal – 27, exploratory thoracotomy – 2. Gastric pull-up 49 (cervical anastomosis – 46; thoracic - 3); cervical oesofagocoloplasty -1.
Results: Pathologic staging: complete remission - 8; Ib – 3; IIa – 9; IIb - 4; IIa – 11; IIIb -2; IIIc – 10; IV – 1; non-stageable - 3. Major complications: 37%. Resectability: 96% (50/52). Mortality: 4th week - 6%; in-hospital - 14%. Median survival 18 months [3-80]. Survival Curves (Kaplan-Meier): 2 years - 47%; 5 years - 19% (transthoracic vs transhiatal p > 0.05).
Discussion: Selection of surgical approach based on the anatomic location of the tumour regarding the carina was safe, the resectability was high and similar when a transthoracic or a transhiatal was planed and carry-on.
Conclusions: In this series of oesophageal cancer patients, in advanced pathologic condition (52% p Stages III/IV) the overall survival was similar for transthoracic and transhiatal. Neo-adjuvant treatments definitively contributed to enhance resectability.


Keywords: Esophagectomy; Laparoscopy; Esophageal Neoplasms/surgery; Thoracotomy.

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Author Biographies

Paulo Costa, Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.

Rui Esteves, Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.

Patrícia Lages, Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.

Filipa Ferreira, Clínica Universitária de Cirurgia I. Faculdade de Medicina. Universidade de Lisboa. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.

Published

2014-10-25

How to Cite

1.
Costa P, Esteves R, Lages P, Ferreira F. Esophageal Cancer: Surgical Strategies. Acta Med Port [Internet]. 2014 Oct. 25 [cited 2024 Nov. 23];27(5):593-600. Available from: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/5159