Impacto da Aplicação do Programa ERAS na Cirurgia Colorrectal de um Centro Hospitalar Terciário

Autores

  • Catarina Lopes Surgery Department. Centro Hospitalar e Universitário de Coimbra. Coimbra. Faculty of Medicine. University of Coimbra. Coimbra.
  • Mariana Vaz Gomes Centro Hospitalar Universitário Coimbra https://orcid.org/0000-0001-6894-775X
  • Manuel Rosete Surgery Department. Centro Hospitalar e Universitário de Coimbra. Coimbra. Faculty of Medicine. University of Coimbra. Coimbra.
  • Ana Almeida Anaesthesiology Department. Centro Hospitalar e Universitário de Coimbra. Coimbra.
  • Luisa Isabel Silva Anaesthesiology Department. Centro Hospitalar e Universitário de Coimbra. Coimbra. https://orcid.org/0000-0002-4574-819X
  • José Guilherme Tralhão Surgery Department. Centro Hospitalar e Universitário de Coimbra. Coimbra. Faculty of Medicine. University of Coimbra. Coimbra. Coimbra Institute for Clinical and Biomedical Research. Area of Environment Genetics and Oncobiology. Faculty of Medicine. University of Coimbra. Coimbra.

DOI:

https://doi.org/10.20344/amp.18284

Resumo

Introdução: Os benefícios do programa multimodal Enhanced Recovery After Surgery® (ERAS) têm sido descritos em todo o mundo. A adoção de várias estratégias peri-operatórias traduz-se numa melhoria dos cuidados de saúde prestados com ganhos para o doente e para a instituição. O objetivo deste estudo foi reportar os resultados da implementação do programa ERAS® na cirurgia colorretal num hospital terciário.
Material e Métodos: Neste estudo unicêntrico observacional foram incluídos 534 doentes submetidos a cirurgia colorretal entre dezembro 2018 e maio de 2021. Foram criados dois grupos: antes e depois da implementação do programa ERAS® com o objetivo primário de comparar a morbilidade aos 30 dias. Foi também avaliado o tempo de internamento, a taxa de reinternamento, reintervenção e a mortalidade entre os grupos.
Resultados: O grupo pré-ERAS era constituído por 102 doentes e o grupo ERAS por 432 doentes. Verificou-se uma redução significativa na morbilidade aos 30 dias (37,3% vs 26,5%, p < 0,05), no tempo de internamento (7 dias vs 5 dias, p < 0,001) e na taxa de readmissão (12,9% vs 6%, p < 0,05) após a implementação do programa.
Conclusão: O protocolo ERAS® na cirurgia colorretal foi implementado com sucesso e segurança no nosso hospital, contribuindo para uma melhoria dos cuidados peri-operatórios prestados aos doentes.

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Referências

Ljungqvist O, Scott M, Fearon KC. Enhanced recovery after surgery a review. JAMA Surg. 2017;152:292–8.

Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, et al. Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Clin Nutr.2012;31:783–800.

Nygren J, Thacker J, Carli F, Fearon KC, Norderval S, Lobo DN, et al. Enhanced Recovery After Surgery Society. Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. Clin Nutr. 2012;31:801-16.

Kaye A, Urman R, Rappaport Y, Siddaiah H, Cornett E, Belani K, et al. Multimodal analgesia as an essential part of enhanced recovery protocols in the ambulatory settings. J Anaesthesiol Clin Pharmacol. 2019;35:40.

Feldheiser A, Aziz O, Baldini G, Cox BP, Fearon KC, Feldman LS, et al. Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice. Acta Anaesthesiol Scand. 2016;60:289–334.

Lohsiriwat V. Enhanced recovery after surgery vs conventional care in emergency colorectal surgery. World J Gastroenterol. 2014;20:13950–5.

Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J. Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg. 2011;146:571–7.

Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240:205-13.

Bragg D, El-Sharkawy AM, Psaltis E, Maxwell-Armstrong CA, Lobo DN. Postoperative ileus: Recent developments in pathophysiology and management. Clin Nutr. 2015;34:367-76.

Berríos-Torres SI, Umscheid CA, Bratzler DW, Leas B, Stone EC, Kelz RR, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection, 2017. JAMA Surg. 2017;152:784–91.

Ban K, Berian J, Ko C. Does implementation of Enhanced Recovery After Surgery (ERAS) protocols in colorectal surgery improve patient outcomes? Clin Colon Rectal Surg. 2019;32:109–13.

Scott MJ, Baldini G, Fearon KC, Feldheiser A, Feldman LS, Gan TJ, et al. Enhanced Recovery after Surgery (ERAS) for gastrointestinal surgery, part 1: Pathophysiological considerations. Acta Anaesthesiol Scand. 2015;59:1212–31.

Shida D, Tagawa K, Inada K, Nasu K, Seyama Y, Maeshiro T, et al. Enhanced Recovery After Surgery (ERAS) protocols for colorectal cancer in Japan. BMC Surg. 2015;15:90.

Tavis SE, Kennedy GD. Postoperative complications: looking forward to a safer future. Clin Colon Rectal Surg. 2016;29:246-52.

Harnsberger C, Maykel J, Alavi K. Postoperative ileus. Clin Colon Rectal Surg. 2019;32:166–70.

Pak H, Maghsoudi LH, Soltanian A, Gholami F. Surgical complications in colorectal cancer patients. Ann Med Surg. 2020;55:13–8.

Ju YU, Min BW. A review of bowel preparation before colorectal surgery. Ann Coloproctology. 2021;37:75–84.

Toh JW, Harlaar J, Di Re A, Pathmanathan N, El Khoury T, Ctercteko G. Understanding the role of mechanical bowel preparation and oral antibiotics prior to elective colorectal surgery. Ann Laparosc Endosc Surg. 2019;4:47.

Liu H, Yang P, Han S, Zhang Y, Zhu H. The application of enhanced recovery after surgery and negative-pressure wound therapy in the perioperative period of elderly patients with colorectal cancer. BMC Surg. 2021;21:336.

Ceretti AP, Maroni N, Longhi M, Giovenzana M, Santambrogio R, Barabino M, et al. Risk factors for prolonged postoperative ileus in adult patients undergoing elective colorectal surgery: an observational cohort study. Rev Recent Clin Trials. 2018;13:295–304.

Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M. Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg. 2014;38:1531–41.

Ripollés-Melchor J, Fuenmayor-Varela ML de, Criado Camargo S, Jerez Fernández P, Contreras del Barrio Á, Martínez-Hurtado E, et al. Enhanced recovery after surgery protocol versus conventional perioperative care in colorectal surgery. A single center cohort study. Braz J Anesthesiol Engl Ed. 2018;68:358–68.

Lee TH, Marcantonio ER, Mangione CM, Thomas EJ, Polanczyk CA, Cook EF, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999;100:1043-9.

Schenning KJ, Deiner SG. Postoperative delirium in the geriatric patient. Anesthesiol Clin. 2015;33:505–16.

Thiele RH, Rea KM, Turrentine FE, Friel CM, Hassinger TE, Goudreau BJ, et al. Standardization of care: Impact of an enhanced recovery protocol on length of stay, complications, and direct costs after colorectal surgery. J Am Coll Surg. 2015;220:430–43.

Carrão A, Ribeiro D, Manso M, Oliveira J, Féria L, Ghira M, et al. ERAS® program in a Portuguese hospital: results from elective colorectal surgery after one year of implementation. Acta Med Port. 2020;33:568–75.

Varadhan KK, Neal KR, Dejong CH, Fearon KC, Ljungqvist O, Lobo DN. The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials. Clin Nutr. 2010;29:434–40.

Batool F, Collins SD, Albright J, Ferraro J, Wu J, Krapohl GL, et al. A regional and national database comparison of colorectal outcomes. JSLS. 2018;22:e2018.00031.

Zhuang C Le, Ye XZ, Zhang XD, Chen BC, Yu Z. Enhanced recovery after surgery programs versus traditional care for colorectal surgery: a metaanalysis of randomized controlled trials. Dis Colon Rectum. 2013;56:667–78.

Miskovic D, Ni M, Wyles SM, Tekkis P, Hanna GB. Learning curve and case selection in laparoscopic colorectal surgery: systematic review and international multicenter analysis of 4852 Cases. Dis Colon Rectum. 2012;55:1300–10.

Walter CJ, Maxwell-Armstrong C, Pinkney TD, Conaghan PJ, Bedforth N, Gornall CB, et al. A randomised controlled trial of the efficacy of ultrasoundguided transversus abdominis plane (TAP) block in laparoscopic colorectal surgery. Surg Endosc. 2013;27:2366–72.

Barletta JF, Asgeirsson T, Senagore AJ. La influencia de las dosis de opioides por via intravenosa sobre la oclusión intestinal postoperatoria. Ann Pharmacother. 2011;45:916–23.

Arrick L, Mayson K, Hong T, Warnock G. Enhanced recovery after surgery in colorectal surgery: Impact of protocol adherence on patient outcomes. J Clin Anesth. 2019;55:7–12.

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Publicado

2022-10-04

Como Citar

1.
Lopes C, Vaz Gomes M, Rosete M, Almeida A, Silva LI, Tralhão JG. Impacto da Aplicação do Programa ERAS na Cirurgia Colorrectal de um Centro Hospitalar Terciário. Acta Med Port [Internet]. 4 de Outubro de 2022 [citado 23 de Dezembro de 2024];36(4):254-63. Disponível em: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/18284

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