Pamidronato dissódico (APD) no tratamento das metástases ósseas.

Autores

  • L Costa Serviço de Medicina I, Hospital de Santa Maria, Lisboa.
  • C Moreira
  • E B da Costa

DOI:

https://doi.org/10.20344/amp.3059

Resumo

Diphosphonates are potent inhibitors of bone resorption, they have been evaluated in several clinical trials for bone metastases. We performed a clinical study to evaluate the therapeutic effect of Disodium Pamidronate over pain and radiologic evolution in bone metastases (Breast Cancer and Multiple Myeloma patients). The results regarding the first 10 patients concluded that there is good drug tolerability and significant analgesic activity in 6 patients, with sclerosis of lytic skull lesions in one breast cancer patient.

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1.
Costa L, Moreira C, da Costa EB. Pamidronato dissódico (APD) no tratamento das metástases ósseas. Acta Med Port [Internet]. 27 de Fevereiro de 1993 [citado 30 de Junho de 2024];6(2):71-3. Disponível em: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/3059

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