Hipertiroidismo por secreção inapropriada não tumoral de TSH.

Autores

  • A Agapito Unidade de Endocrinologia, Hospital Curry Cabral, Lisboa.
  • L Guerra
  • A Afonso
  • F Fonseca
  • F Malheiro
  • C da Costa

DOI:

https://doi.org/10.20344/amp.3203

Resumo

We report a case of hyperthyroidism due to non-neoplastic inappropriate thyrotrophin secretion in a 31 year old woman. Increased T3 and THS levels after thyroidectomy led us to suspect the diagnose. Serum levels were further increased by TRH and only partially suppressed by triiodothyronine and computerised axial tomography showed a normal sellar region. These features are characteristic of inappropriate TSH secretion due to thyrotroph resistance to thyroid hormones. Bromocriptine and octreotide were ineffective in lowering TSH levels. Pregnancy and breastfeeding postponed 3,5,3'-triiodothyroacetic acid therapy.

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1.
Agapito A, Guerra L, Afonso A, Fonseca F, Malheiro F, da Costa C. Hipertiroidismo por secreção inapropriada não tumoral de TSH. Acta Med Port [Internet]. 27 de Fevereiro de 1992 [citado 30 de Junho de 2024];5(2):104-6. Disponível em: https://actamedicaportuguesa.com/revista/index.php/amp/article/view/3203

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